Best Practice in Treatment

Best practice in treatment for Profound Autism means using approaches that are evidence-based, individualized, person-centered, multidisciplinary, and designed with the whole lifespan in mind. It including building supports that respect the person’s dignity and truly improve their quality of life, both now and in the future. Unlike fads or unproven “quick fixes,” best practice relies on scientifically supported methods that adapt to each person’s unique needs and values. This ensures that treatment choices are meaningful, effective, and sustainable over time.

Treatment that works.

When we say these treatments are evidence-based, it means they are supported by solid scientific research — not just personal stories or marketing claims. Researchers have carefully studied these methods in real-world settings and shown that they can reliably help people with autism learn skills, improve communication, and enhance quality of life. Evidence-based does not mean “one-size-fits-all,” but it does mean families can feel confident that the approaches are safe, effective, and worth the time and effort.

  • Applied Behavior Analysis (ABA) is an evidence-based approach that focuses on teaching meaningful skills and reducing challenging behaviors by understanding why behaviors occur. It emphasizes building functional, real-life skills — such as communication, daily living, and social engagement — that improve quality of life.

    Modern best-practice ABA avoids rigid or compliance-only methods and instead uses assent-based strategies and trauma-informed care, giving the person choice and respecting their comfort. Treatment should should actively involve caregivers/family to guide goals to ensure treatment supports both present needs and a meaningful future.

  • Speech and language therapy helps people with Profound Autism find their voice — whether through spoken words, sign language, or augmentative and alternative communication (AAC) tools like devices and picture systems. The goal is not just speech, but true communication: being able to express needs, make choices, and connect with others.

    Best practice means tailoring communication supports to the individual, teaching partners (family, teachers, caregivers) how to respond effectively, and ensuring the person has reliable ways to be understood in every environment.

  • Occupational therapy supports independence by building the skills needed for everyday life — from eating, dressing, and hygiene to managing sensory challenges and fine motor tasks. For individuals with Profound Autism, OT often blends skill-building with environmental supports, making activities more accessible and comfortable.

    Best-practice OT works in close partnership with families to identify priorities that truly matter for daily quality of life and long-term independence.

  • Physical therapy helps individuals with Profound Autism develop and maintain mobility, strength, balance, and coordination. This can mean anything from learning to walk more safely to building endurance for community outings.

    Best practice means integrating PT goals into everyday life — so movement skills directly support participation at home, school, and in the community. PT can also help prevent secondary health problems and support lifelong physical well-being.

  • Using Functional Analysis (FA), Practical Functional Assessment (PFA) and Skill-Based Treatment (SBT) are evidence-based ways to address dangerous or challenging behaviors. Instead of relying on punishment, they focus on identifying the function of the behavior and teaching safe, positive skills that meet the same need.

    Best practice in this area is collaborative, compassionate, and future-focused — keeping dignity at the center while giving the person more effective tools to navigate their world.

Recommended Standards and Guidelines for Evidence-Based Practice

NCAEP Review Findings (National Clearinghouse on Autism Evidence & Practice)
The NCAEP builds on NPDC’s work by offering an updated systematic review of autism intervention research from 1990 through 2017. The 2020 report identifies 28 evidence-based practices and provides an interactive Evidence-Based Practice Database to help users search by age range and domain.

ASHA Autism Practice Portal
The American Speech-Language-Hearing Association’s Practice Portal offers curated, peer-reviewed resources for clinicians and families. Their autism section includes evidence-based information on assessment, intervention strategies, AAC, and communication supports—designed to facilitate informed clinical decision-making.

ABAI Position Statements
The Association for Behavior Analysis International issues formal position statements that guide ethical behavior-analytic practices. Notable examples include opposition to facilitated communication and contingent electric skin shock (CESS)—demonstrating a clear commitment to science-driven, ethical treatment.

AOTA Practice Guidelines
The American Occupational Therapy Association develops practice guidelines based on systematic reviews and expert consensus. These guidelines translate research findings into actionable recommendations and tools to guide occupational therapy care for autistic individuals.


Additional Recommended Guidelines

  • CASP ABA Practice & Organizational Guidelines: Standards for safe, ethical, and effective ABA at both provider and organizational levels.

  • UK NICE Guidelines: Comprehensive, evidence-based guidance on diagnosis, management, and support across the lifespan.

  • SCERTS Model & TEACCH Approach: Holistic frameworks centered on communication, emotional regulation, family collaboration, and structured environments.

  • Ireland Assessment Guidelines: Promotes structured, multidisciplinary evaluation across settings.

  • California DDS Best Practices: Regional example of foundational service design and recommendations for ASD-related supports.

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